Genetic & Immunological Aspects of Diabetes

It is believed that a large proportion of cases of type 1 diabetes result from the autoimmune destruction of the pancreatic β cells. Genetic marker that makes person susceptible to diabetes is located on chromosome 6, and it’s an HLA (human leukocyte antigen) complex. Several HLA complexes have been connected to type 1 diabetes, and if the people have one or more of those, may develop type 1diabities. Fulminant type 1 diabetes (FT1D) is a novel subtype of type 1 diabetes characterized by extremely rapid onset and complete deficiency of insulin due to the destruction of pancreatic β cells. It has been proposed that locally produced MCP-1 may be involved in the development of diabetic nephropathy
A study also suggests that diabetes might be linked to genetics. To date, numerous mutations have been shown to affect type 2 diabetes risks. Genes associated with type 2 diabetes are:
  • TCF7L2, which affects insulin secretion and glucose production
  • ABCC8, which helps regulate insulin
  • CAPN10, which is associated with type 2 diabetes risk in Mexican-Americans
  • GLUT2, which helps move glucose into the pancreas
  • GCGR, a glucagon hormone involved in glucose regulation

    Related Conference of Genetic & Immunological Aspects of Diabetes

    February 24-25, 2025

    34th European Diabetes Congress

    London, UK
    March 10-11, 2025

    4th Global Summit on Physiology and Metabolism of Thyroid

    Singapore City, Singapore
    March 17-18, 2025

    5th European Endocrinology and Diabetes Congress

    Paris, France
    April 10-11, 2025

    5th World Congress on Endocrine and Diabetes

    Dubai, UAE
    April 10-11, 2025

    4th International Summit on Hormonal Disorders

    Dubai, UAE
    May 19-20, 2025

    6th World Summit on Diabetes

    Rome, Italy
    June 04-05, 2025

    4th World Congress on Diabetes and Pediatric Endocrinology

    Edinburgh, Scotland
    July 29-30, 2025

    15th World Congress on Endocrinology and Diabetes

    Aix-en-Provence, France
    September 08-09, 2025

    3rd World congress and Expo on Diabetes

    Frankfurt, Germany
    November 20-21, 2025

    21st World Congress on Endocrinology & Diabetes

    Aix-en-Provence, France

    Genetic & Immunological Aspects of Diabetes Conference Speakers

      Recommended Sessions

      Related Journals

      Are you interested in